Publications

§ Equal contribution, # Corresponding author

Selected Articles

• Sexual dimorphic pattern of renal transporters and channels in spontaneously hypertensive rats
  Lingyun (Ivy) Xiong§, Ariel Finch§, Donna L. Ralph, Babatunde D. Anidu, Louise C. Evans#, Alicia A. McDonough# (In Submission).

• Life in the fast lane: Functional consequences of male-female dynamic differences in the renal autoregulation of flow
  Lingyun (Ivy) Xiong#, Alan Garfinkel#, Kevin M. Bennett, Edwin J. Baldelomar, Lauryn Brown, Kate Barrows, Volker Vallon, Aurelie Edwards, Alicia A. McDonough, Natalie Porat-Shliom#, Eric J. Deeds#. bioRxiv, 2025 (Under Revision). DOI: 10.1101/2025.09.12.675896

• Sex differences in renal transporters: assessment and functional consequences
  Alicia A. McDonough#, Autumn N. Harris, Lingyun (Ivy) Xiong, Anita T. Layton.
  Nat Rev Nephrol, 2024;20(1):21-36. DOI: 10.1038/s41581-023-00757-2 (PDF)

• Direct androgen receptor control of sexually dimorphic gene expression in the mammalian kidney
  Lingyun Xiong§, Jing Liu§, Sueng Yub Han, Kari Koppitch, Jin-Jin Guo, Megan Rommelfanger, Zhen Miao, Fan Gao, Ingileif Hallgrimsdottir, Lior Pachter, Junhyong Kim, Adam L. MacLean, Andrew P. McMahon#.
  Dev Cell, 2023;58(21):2338-2358.e5. DOI: 10.1016/j.devcel.2023.08.010 (PDF)
  ^Highlighted by: Multimodal characterization of sexual dimorphism in the mammalian kidney.
  Haikuo Li, Benjamin D. Humphreys. Kidney Int, 2024;105(4), 653–655.

• Are physiological oscillations physiological?
  Lingyun (Ivy) Xiong, Alan Garfinkel#.
  J Physiol, 2023 Aug 25 (Online ahead of print). DOI: 10.1113/JP285015 (PDF)

• A common pathway to cancer: Oncogenic mutations abolish p53 oscillations
  Lingyun (Ivy) Xiong, Alan Garfinkel#.
  Prog Biophys Mol Biol, 2022 Oct;174:28-40. DOI: 10.1016/j.pbiomolbio.2022.06.002 (PDF)

Additional Publications

• Measuring nephron number in the healthy and diabetic rat kidney in vivo using MRI without contrast agents
  Edwin J. Baldelomar, Jennifer R. Charlton, Shella Keilhoz, Benjamin Kohn, Leslie D. Wilson, Lingyun (Ivy) Xiong, Alan Garfinkel, and Kevin M. Bennett#.
  AJP Renal Physiol, 2026 (In Press). DOI: 10.1152/ajprenal.00088.2026

• Gene regulatory network inference with popInfer reveals dynamic regulation of hematopoietic stem cell quiescence
  Megan K Rommelfanger, Marthe Behrends, Yulin Chen, Jonathan Martinez, Nikith Kurella,
  Nino Geisler, Deepthi Guturu, Martin Bens, Lingyun Xiong, Zijin Xiang, K Lenhard Rudolph,
  Adam L. MacLean#.
  iScience, 2025;28(12):114010. DOI: 10.1016/j.isci.2025.114010 (PDF)

• Abstract: Tubuloglomerular feedback system dynamically regulates cardiorenal crosstalk
  Lingyun Xiong#, Alicia A. McDonough.
  Hypertension, 2025;82(Suppl_1):093. DOI: 10.1161/hyp.82.suppl_1.093

• Abstract: Functional coupling of cellular metabolism and renal hemodynamics underlies kidney sex differences
  Lingyun Xiong#, Alan Garfinkel, Kate Barrows, Lauryn Brown, Natalie Porat-Shliom, and Eric J. Deeds.
  Physiology, 2025;40(S1):0755. DOI: 10.1152/physiol.2025.40.S1.0755

• Studying the effects of oral contraceptives on coagulation using a mathematical model
  Amy Kent, Karin Leiderman#, Anna C. Nelson, Suzanne Sindi, Melissa M. Stadt,
  Lingyun Xiong, Ying Zhang.
  Mathematical Modeling for Women’s Health (Springer Nature Switzerland), 2024;166:83–132. DOI: 10.1007/978-3-031-58516-6_4 (PDF)

• Abstract: Sexual dimorphism in renal metabolism, hemodynamics and diseases
  Lingyun Xiong#, Alan Garfinkel, Eric J. Deeds.
  Physiology, 2024;39(S1):1234. DOI: 10.1152/physiol.2024.39.S1.1234

• Abstract: Sex differences in proximal tubule metabolism influence hemodynamics and salt reabsorption to mediate dimorphic susceptibility to kidney diseases
  Lingyun Xiong#, Adam L. MacLean, Andrew P. McMahon.
  Physiology, 2023;38(S1):5731763. DOI: 10.1152/physiol.2023.38.S1.5731763

• Genomic hallmarks and therapeutic implications of G0 cell cycle arrest in cancer
  Anna J. Wiecek, Stephen J. Cutty, Daniel Kornai, Mario Parreno-Centeno, Lucie E. Gourmet, Guidantonio Malagoli Tagliazucchi, Daniel H. Jacobson, Ping Zhang, Lingyun Xiong, Gareth Bond, Alexis R. Barr, Maria Secrier#.
  Genome Biol, 2023;24(1):128. DOI: 10.1186/s13059-023-02963-4 (PDF)

• Influence of inherited genetic variants on risk, biology and prognosis of common cancers
  Lingyun Xiong
  PhD thesis, University of Oxford, 2021

• Germline and somatic genetic variants in the p53 pathway interact to affect cancer risk, progression, and drug response
  Ping Zhang, Isaac Kitchen-Smith, Lingyun Xiong, Giovanni Stracquadanio, Katherine Brown, Philipp Richter, Marsha Wallace, Elisabeth Bond, Natasha Sahgal, Samantha Moore, Svanhild Nornes, Sarah De Val, Mirvat Surakhy, David Sims, Xuting Wang, Douglas A Bell, Jorge Zeron-Medina, Yanyan Jiang, Anderson Ryan, Joanna Selfe, Janet Shipley, Siddhartha Kar, Paul Pharoah, Chey Loveday, Rick Jansen, Lukasz F. Grochola, Claire Palles, Andrew Protheroe, Val Millar, Daniel Ebner, Meghana Pagadala, Sarah P Blagden, Tim Maughan, Enric Domingo, Ian Tomlinson, Clare Turnbull, Hannah Carter, Gareth Bond#.
  Cancer Res, 2021;81:1667–1680. DOI: 10.1158/0008-5472.CAN-20-0177 (PDF)

• Heritable genetic variants in key cancer genes link cancer risk with anthropometric traits
  Matteo Di Giovannantonio, Benjamin H.L. Harris, Ping Zhang, Isaac Kitchen-Smith, Lingyun Xiong, Natasha Sahgal, Giovanni Stracquadanio, Marsha Wallace, Sarah Blagden, Simon Lord, David A. Harris, Adrian Harris, Francesca M. Buffa, Gareth Bond#.
  J Med Genet, 2020;0:1–8. DOI: 10.1136/jmedgenet-2019-106799

• SALL4 promotes glycolysis and chromatin remodelling via modulating HP1α-Glut1 pathway
  Jinchul Kim, Shuxiang Xu, Lingyun Xiong, Lily Yu, Xuemei Fu, Yang Xu#.
  Oncogene, 2017;36(46):6472–6479. DOI: 10.1038/onc.2017.265 (PDF)

Preprints

• Learning feedback loops in transcriptome network during cell fate transition
  Lingyun Xiong#, William A. Schoenberg, Jeremy D. Swartz.
  bioRxiv, 2024. DOI: 10.1101/2020.06.24.169490v2

Complete List of Published Work in My Bibliography: https://www.ncbi.nlm.nih.gov/myncbi/lingyun.xiong.1/bibliography/public/